Acne Vulgaris is the most common human skin disease, affecting quality of life of millions worldwide. In spite of heroic basic and applied research efforts, we still lack indisputably curative anti-acne agents, which target multiple pathogenetic steps of acne (sebum overproduction, unwanted sebocyte proliferation, inflammation) and, moreover, which possess favourable side effect profiles. Investigations over the last two decades have confirmed unambiguously that the human body expresses such receptors, which are able to specifically bind and recognise characteristic terpene-phenol compounds of the infamous plant Cannabis sativa, collectively referred to as phytocannabinoids.
A recent study posted to the Journal of Clinical Investigation found that CBD helps to lower the production of sebum that leads to acne, partly because of its anti-inflammatory effect on the body.
CBD can be used to affect the output of oils in the skin and hair. Specifically, CBD inhibits the lipid production in skin cells, making it an effective preventative for acne. However, manipulating this system can also be used to increase output of sebum as well to prevent dry skin issues.
The anti-inflammatory properties of CBD can also control the other effects of acne because the skin around the spot is intensely inflamed. Pimples are effectively infections, and it is best to treat them as such. CBD can act as an antibacterial agent, decreasing the likelihood of further acne in the future.